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Muscle-derived stem/progenitor cell dysfunction in Zmpste24-deficient progeroid mice limits muscle regeneration

INTRODUCTION: Loss of adult stem cell function during aging contributes to impaired tissue regeneration. Here, we tested the aging-related decline in regeneration potential of adult stem cells residing in the skeletal muscle. METHODS: We isolated muscle-derived stem/progenitor cells (MDSPCs) from pr...

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Detalles Bibliográficos
Autores principales: Song, Minjung, Lavasani, Mitra, Thompson, Seth D, Lu, Aiping, Ahani, Bahar, Huard, Johnny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706820/
https://www.ncbi.nlm.nih.gov/pubmed/23531345
http://dx.doi.org/10.1186/scrt183