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Oxidative stress-induced Notch1 signaling promotes cardiogenic gene expression in mesenchymal stem cells

INTRODUCTION: Administration of bone marrow-derived mesenchymal stem cells (MSCs) after myocardial infarction (MI) results in modest functional improvements. However; the effect of microenvironment changes after MI, such as elevated levels of oxidative stress on cardiogenic gene expression of MSCs,...

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Detalles Bibliográficos
Autores principales: Boopathy, Archana V, Pendergrass, Karl D, Che, Pao Lin, Yoon, Young-Sup, Davis, Michael E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706823/
https://www.ncbi.nlm.nih.gov/pubmed/23597145
http://dx.doi.org/10.1186/scrt190