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DNA-dependent protein kinase and DNA repair: relevance to Alzheimer's disease

The pathological hallmark of Alzheimer's disease (AD), the leading cause of senile dementia, involves region-specific neuronal death and an accumulation of neuronal and extracellular lesions termed neurofibrillary tangles and senile plaques, respectively. One of the biochemical abnormalities ob...

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Detalles Bibliográficos
Autor principal: Kanungo, Jyotshna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706827/
https://www.ncbi.nlm.nih.gov/pubmed/23566654
http://dx.doi.org/10.1186/alzrt167