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Are clinical trials dealing with severe infection fitting routine practices? Insights from a large registry

INTRODUCTION: Guidelines dealing with severe sepsis and septic shock mostly rely on randomized controlled trials (RCTs) to ensure the best standards of care for patients. However, patients included in high-quality studies may differ from the routine population and alter external validity of recommen...

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Detalles Bibliográficos
Autores principales: Claessens, Yann-Erick, Aegerter, Philippe, Boubaker, Hamdi, Guidet, Bertrand, Cariou, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706971/
https://www.ncbi.nlm.nih.gov/pubmed/23705948
http://dx.doi.org/10.1186/cc12734