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CD70–CD27 ligation between neural stem cells and CD4(+) T cells induces Fas–FasL-mediated T-cell death

INTRODUCTION: Neural stem cells (NSCs) are among the most promising candidates for cell replacement therapy in neuronal injury and neurodegenerative diseases. One of the remaining obstacles for NSC therapy is to overcome the alloimmune response on NSCs by the host. METHODS: To investigate the mechan...

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Detalles Bibliográficos
Autores principales: Lee, Eun Mi, Hurh, Sunghoon, Cho, Bumrae, Oh, Kook-Hwan, Kim, Seung U, Surh, Charles D, Sprent, Jonathan, Yang, Jaeseok, Kim, Jae Young, Ahn, Curie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706991/
https://www.ncbi.nlm.nih.gov/pubmed/23692980
http://dx.doi.org/10.1186/scrt206