Spasmolytic Effect of Caulerpine Involves Blockade of Ca(2+) Influx on Guinea Pig Ileum

In this work, we investigated the spasmolytic effect of caulerpine, a bisindole alkaloid isolated from marine algae of the Caulerpa genus, on guinea pig ileum. Our findings indicated that caulerpine inhibited phasic contractions induced by carbachol (IC(50) = 7.0 ± 1.9 × 10(−5) M), histamine (IC(50)...

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Detalles Bibliográficos
Autores principales: Cavalcante-Silva, Luiz Henrique Agra, de Carvalho Correia, Ana Carolina, Barbosa-Filho, José Maria, Araújo da Silva, Bagnólia, de Oliveira Santos, Bárbara Viviana, de Lira, Daysianne Pereira, Ferreira Sousa, Jéssica Celestino, de Miranda, George Emmanuel C., de Andrade Cavalcante, Fabiana, Alexandre-Moreira, Magna Suzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707161/
https://www.ncbi.nlm.nih.gov/pubmed/23670534
http://dx.doi.org/10.3390/md11051553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707161/
https://www.ncbi.nlm.nih.gov/pubmed/23670534
http://dx.doi.org/10.3390/md11051553

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