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Heparanase—A Link between Coagulation, Angiogenesis, and Cancer

Heparanase that was cloned from and is abundant in the placenta is implicated in cell invasion, tumor metastasis, and angiogenesis. Recently we have demonstrated that heparanase may also affect the hemostatic system in a non-enzymatic manner. Heparanase was shown to up-regulate tissue factor (TF) ex...

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Detalles Bibliográficos
Autores principales: Nadir, Yona, Brenner, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rambam Health Care Campus 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707414/
https://www.ncbi.nlm.nih.gov/pubmed/23908827
http://dx.doi.org/10.5041/RMMJ.10069