Hybrid error correction and de novo assembly of single-molecule sequencing reads

Emerging single-molecule sequencing instruments can generate multi-kilobase sequences with the potential to dramatically improve genome and transcriptome assembly. However, the high error rate of single-molecule reads is challenging, and has limited their use to resequencing bacteria. To address thi...

Descripción completa

Detalles Bibliográficos
Autores principales: Koren, Sergey, Schatz, Michael C., Walenz, Brian P., Martin, Jeffrey, Howard, Jason, Ganapathy, Ganeshkumar, Wang, Zhong, Rasko, David A., McCombie, W. Richard, Jarvis, Erich D., Phillippy, Adam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707490/
https://www.ncbi.nlm.nih.gov/pubmed/22750884
http://dx.doi.org/10.1038/nbt.2280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707490/
https://www.ncbi.nlm.nih.gov/pubmed/22750884
http://dx.doi.org/10.1038/nbt.2280

Ejemplares similares