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Sox2 suppresses the invasiveness of breast cancer cells via a mechanism that is dependent on Twist1 and the status of Sox2 transcription activity

BACKGROUND: Sox2, an embryonic stem cell marker, is aberrantly expressed in a subset of breast cancer (BC). While the aberrant expression of Sox2 has been shown to significantly correlate with a number of clinicopathologic parameters in BC, its biological significance in BC is incompletely understoo...

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Detalles Bibliográficos
Autores principales: Wu, Fang, Ye, Xiaoxia, Wang, Peng, Jung, Karen, Wu, Chengsheng, Douglas, Donna, Kneteman, Norman, Bigras, Gilbert, Ma, Yupo, Lai, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707762/
https://www.ncbi.nlm.nih.gov/pubmed/23815808
http://dx.doi.org/10.1186/1471-2407-13-317