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Frizzled-8 receptor is activated by the Wnt-2 ligand in non-small cell lung cancer

BACKGROUND: Wnt-2 plays an oncogenic role in cancer, but which Frizzled receptor(s) mediates the Wnt-2 signaling pathway in lung cancer remains unclear. We sought to (1) identify and evaluate the activation of Wnt-2 signaling through Frizzled-8 in non-small cell lung cancer, and (2) test whether a n...

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Detalles Bibliográficos
Autores principales: Bravo, Dawn T, Yang, Yi-Lin, Kuchenbecker, Kristopher, Hung, Ming-Szu, Xu, Zhidong, Jablons, David M, You, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707790/
https://www.ncbi.nlm.nih.gov/pubmed/23815780
http://dx.doi.org/10.1186/1471-2407-13-316