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Correlation of dynamic changes in γ-H2AX expression in peripheral blood lymphocytes from head and neck cancer patients with radiation-induced oral mucositis

BACKGROUND: To evaluate the role of γ-H2AX in peripheral blood lymphocytes (PBLs) as a predictive biomarker of the severity of oral mucositis (OM) in head and neck cancer (HNC) patients with receiving radiotherapy. METHODS: In vitro assays for evaluating DNA damage and repair kinetics were performed...

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Detalles Bibliográficos
Autores principales: Li, Ping, Du, Cheng-run, Xu, Wen-cai, Shi, Ze-liang, Zhang, Qing, Li, Zhao-bin, Fu, Shen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707835/
https://www.ncbi.nlm.nih.gov/pubmed/23803252
http://dx.doi.org/10.1186/1748-717X-8-155