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NGF-Induced Cell Differentiation and Gene Activation Is Mediated by Integrative Nuclear FGFR1 Signaling (INFS)

Nerve growth factor (NGF) is the founding member of the polypeptide neurotrophin family responsible for neuronal differentiation. To determine whether the effects of NGF rely upon novel Integrative Nuclear FGF Receptor-1 (FGFR1) Signaling (INFS) we utilized the PC12 clonal cell line, a long-standing...

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Detalles Bibliográficos
Autores principales: Lee, Yu-Wei, Stachowiak, Ewa K., Birkaya, Barbara, Terranova, Christopher, Capacchietti, Mariolina, Claus, Peter, Aletta, John M., Stachowiak, Michal K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707895/
https://www.ncbi.nlm.nih.gov/pubmed/23874817
http://dx.doi.org/10.1371/journal.pone.0068931