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1,25-dihydroxyvitamin D(3) Activates MMP13 Gene Expression in Chondrocytes through p38 MARK Pathway

Osteoarthritis (OA) is the most prevalent degenerative joint disease. The highly regulated balance of matrix synthesis and degradation is disrupted in OA, leading to progressive breakdown of articular cartilage. The molecular events and pathways involved in chondrocyte disfunction of cartilage in OA...

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Detalles Bibliográficos
Autores principales: Chen, Dafu, Li, Yang, Dai, Xuejun, Zhou, Xinhua, Tian, Wei, Zhou, Yixin, Zou, Xuenong, Zhang, Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708044/
https://www.ncbi.nlm.nih.gov/pubmed/23847446
http://dx.doi.org/10.7150/ijbs.6726