RNAsnp: Efficient Detection of Local RNA Secondary Structure Changes Induced by SNPs

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Structural characteristics are essential for the functioning of many noncoding RNAs and cis-regulatory elements of mRNAs. SNPs may disrupt these structures, interfere with their molecular function, and hence cause a phenotypic effect. RNA folding algorithms can provide detailed insights into structu...

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Detalles Bibliográficos
Autores principales: Sabarinathan, Radhakrishnan, Tafer, Hakim, Seemann, Stefan E, Hofacker, Ivo L, Stadler, Peter F, Gorodkin, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Informatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708107/
https://www.ncbi.nlm.nih.gov/pubmed/23315997
http://dx.doi.org/10.1002/humu.22273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708107/
https://www.ncbi.nlm.nih.gov/pubmed/23315997
http://dx.doi.org/10.1002/humu.22273

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