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Establishment of tumor-specific copy number alterations from plasma DNA of patients with cancer

With the increasing number of available predictive biomarkers, clinical management of cancer is becoming increasingly reliant on the accurate serial monitoring of tumor genotypes. We tested whether tumor-specific copy number changes can be inferred from the peripheral blood of patients with cancer....

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Detalles Bibliográficos
Autores principales: Heitzer, Ellen, Auer, Martina, Hoffmann, Eva Maria, Pichler, Martin, Gasch, Christin, Ulz, Peter, Lax, Sigurd, Waldispuehl-Geigl, Julie, Mauermann, Oliver, Mohan, Sumitra, Pristauz, Gunda, Lackner, Carolin, Höfler, Gerald, Eisner, Florian, Petru, Edgar, Sill, Heinz, Samonigg, Hellmut, Pantel, Klaus, Riethdorf, Sabine, Bauernhofer, Thomas, Geigl, Jochen B, Speicher, Michael R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708119/
https://www.ncbi.nlm.nih.gov/pubmed/23319339
http://dx.doi.org/10.1002/ijc.28030