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Centrosome Polarization in T Cells: A Task for Formins

T-cell antigen receptor (TCR) engagement triggers the rapid reorientation of the centrosome, which is associated with the secretory machinery, toward the immunological synapse (IS) for polarized protein trafficking. Recent evidence indicates that upon TCR triggering the INF2 formin, together with th...

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Detalles Bibliográficos
Autores principales: Andrés-Delgado, Laura, Antón, Olga M., Alonso, Miguel Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708132/
https://www.ncbi.nlm.nih.gov/pubmed/23874337
http://dx.doi.org/10.3389/fimmu.2013.00191