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Changes in the sensitivity of GABA(A) current rundown to drug treatments in a model of temporal lobe epilepsy
The pharmacological treatment of mesial temporal lobe epilepsy (mTLE), the most common epileptic syndrome in adults, is still unsatisfactory, as one-third of the patients are or become refractory to antiepileptic agents. Refractoriness may depend upon drug-induced alterations, but the disease per se...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708152/ https://www.ncbi.nlm.nih.gov/pubmed/23874269 http://dx.doi.org/10.3389/fncel.2013.00108 |