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Micronuclei in genotoxicity assessment: from genetics to epigenetics and beyond

Micronuclei (MN) are extra-nuclear bodies that contain damaged chromosome fragments and/or whole chromosomes that were not incorporated into the nucleus after cell division. MN can be induced by defects in the cell repair machinery and accumulation of DNA damages and chromosomal aberrations. A varie...

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Detalles Bibliográficos
Autores principales: Luzhna, Lidiya, Kathiria, Palak, Kovalchuk, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708156/
https://www.ncbi.nlm.nih.gov/pubmed/23874352
http://dx.doi.org/10.3389/fgene.2013.00131