Integrative Omics Analysis Reveals the Importance and Scope of Translational Repression in microRNA-mediated Regulation

MicroRNAs (miRNAs) are key post-transcriptional regulators that inhibit gene expression by promoting mRNA decay and/or suppressing translation. However, the relative contributions of these two mechanisms to gene repression remain controversial. Early studies favor a translational repression-centric...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Halvey, Patrick J., Shyr, Yu, Slebos, Robbert J. C., Liebler, Daniel C., Zhang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708174/
https://www.ncbi.nlm.nih.gov/pubmed/23550052
http://dx.doi.org/10.1074/mcp.M112.025783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708174/
https://www.ncbi.nlm.nih.gov/pubmed/23550052
http://dx.doi.org/10.1074/mcp.M112.025783

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