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Integrative Omics Analysis Reveals the Importance and Scope of Translational Repression in microRNA-mediated Regulation

MicroRNAs (miRNAs) are key post-transcriptional regulators that inhibit gene expression by promoting mRNA decay and/or suppressing translation. However, the relative contributions of these two mechanisms to gene repression remain controversial. Early studies favor a translational repression-centric...

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Detalles Bibliográficos
Autores principales:	Liu, Qi, Halvey, Patrick J., Shyr, Yu, Slebos, Robbert J. C., Liebler, Daniel C., Zhang, Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Biochemistry and Molecular Biology 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708174/ https://www.ncbi.nlm.nih.gov/pubmed/23550052 http://dx.doi.org/10.1074/mcp.M112.025783

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