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Hepatoprotective and Antioxidant Effects of Saponarin, Isolated from Gypsophila trichotoma Wend. on Paracetamol-Induced Liver Damage in Rats

The hepatoprotective potential of saponarin, isolated from Gypsophila trichotoma, was evaluated in vitro/in vivo using a hepatotoxicity model of paracetamol-induced liver injury. In freshly isolated rat hepatocytes, paracetamol (100 μmol) led to a significant decrease in cell viability, increased LD...

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Detalles Bibliográficos
Autores principales: Simeonova, Rumyana, Vitcheva, Vessela, Kondeva-Burdina, Magdalena, Krasteva, Ilina, Manov, Vassil, Mitcheva, Mitka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708395/
https://www.ncbi.nlm.nih.gov/pubmed/23878818
http://dx.doi.org/10.1155/2013/757126