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Timosaponin AIII Suppresses Hepatocyte Growth Factor-Induced Invasive Activity through Sustained ERK Activation in Breast Cancer MDA-MB-231 Cells

Background. The aim of this study was to investigate the mechanisms by which Timosaponin AIII (TAIII) is able to inhibit HGF-induced invasion activity in the triple negative breast cancer cell line MDA-MB-231. Methods. After pretreatment with different concentrations (10(−6)~10(−8) M) of TAIII, the...

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Detalles Bibliográficos
Autores principales: Tsai, Chung-Hsin, Yang, Chu-Wen, Wang, Jir-You, Tsai, Yi-Fang, Tseng, Ling-Ming, King, Kuan-Liang, Chen, Wei-Shone, Chiu, Jen-Hwey, Shyr, Yi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708436/
https://www.ncbi.nlm.nih.gov/pubmed/23878598
http://dx.doi.org/10.1155/2013/421051