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Crystal structure of Schmallenberg orthobunyavirus nucleoprotein–RNA complex reveals a novel RNA sequestration mechanism

Schmallenberg virus (SBV) is a newly emerged orthobunyavirus (family Bunyaviridae) that has caused severe disease in the offspring of farm animals across Europe. Like all orthobunyaviruses, SBV contains a tripartite negative-sense RNA genome that is encapsidated by the viral nucleocapsid (N) protein...

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Detalles Bibliográficos
Autores principales: Dong, Haohao, Li, Ping, Böttcher, Bettina, Elliott, Richard M., Dong, Changjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708532/
https://www.ncbi.nlm.nih.gov/pubmed/23798666
http://dx.doi.org/10.1261/rna.039057.113