A novel insight into the mechanism of mammalian selenoprotein synthesis

The amino acid selenocysteine is encoded by UGA, usually a stop codon, thus requiring a specialized machinery to enable its incorporation into selenoproteins. The machinery comprises the tRNA(Sec), a 3′-UTR mRNA stem–loop termed SElenoCysteine Insertion Sequence (SECIS), which is mandatory for recod...

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Detalles Bibliográficos
Autores principales: Kossinova, Olga, Malygin, Alexey, Krol, Alain, Karpova, Galina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708534/
https://www.ncbi.nlm.nih.gov/pubmed/23788723
http://dx.doi.org/10.1261/rna.036871.112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708534/
https://www.ncbi.nlm.nih.gov/pubmed/23788723
http://dx.doi.org/10.1261/rna.036871.112

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