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A miRNA-responsive cell-free translation system facilitates isolation of hepatitis C virus miRNP complexes

Micro(mi)RNAs are 21- to 23-nt RNAs that regulate multiple biological processes. In association with Argonaute (Ago) proteins and other factors that form the RNA-induced silencing complex (RISC), miRNAs typically bind mRNA 3′ untranslated regions (UTRs) and repress protein production through antagon...

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Detalles Bibliográficos
Autores principales: Bradrick, Shelton S., Nagyal, Simardeep, Novatt, Hilary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708535/
https://www.ncbi.nlm.nih.gov/pubmed/23793894
http://dx.doi.org/10.1261/rna.038810.113