IRF-1 responsiveness to IFN-γ predicts different cancer immune phenotypes

BACKGROUND: Several lines of evidence suggest a dichotomy between immune active and quiescent cancers, with the former associated with a good prognostic phenotype and better responsiveness to immunotherapy. Central to such dichotomy is the master regulator of the acute inflammatory process interfero...

Descripción completa

Detalles Bibliográficos
Autores principales: Murtas, D, Maric, D, De Giorgi, V, Reinboth, J, Worschech, A, Fetsch, P, Filie, A, Ascierto, M L, Bedognetti, D, Liu, Q, Uccellini, L, Chouchane, L, Wang, E, Marincola, F M, Tomei, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708578/
https://www.ncbi.nlm.nih.gov/pubmed/23807161
http://dx.doi.org/10.1038/bjc.2013.335

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708578/
https://www.ncbi.nlm.nih.gov/pubmed/23807161
http://dx.doi.org/10.1038/bjc.2013.335

Ejemplares similares