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Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells
Oxidation of cysteine residues to disulfides drives import of many proteins into the intermembrane space of mitochondria. Recent studies in yeast unraveled the basic principles of mitochondrial protein oxidation, but the kinetics under physiological conditions is unknown. We developed assays to foll...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708723/ https://www.ncbi.nlm.nih.gov/pubmed/23676665 http://dx.doi.org/10.1091/mbc.E12-12-0862 |