Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes

When clonal populations of human cells are exposed to apoptosis-inducing agents, some cells die and others survive. This fractional killing arises not from mutation but from preexisting, stochastic differences in the levels and activities of proteins regulating apoptosis. Here we examine the propert...

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Detalles Bibliográficos
Autores principales: Flusberg, Deborah A., Roux, Jérémie, Spencer, Sabrina L., Sorger, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708725/
https://www.ncbi.nlm.nih.gov/pubmed/23699397
http://dx.doi.org/10.1091/mbc.E12-10-0737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708725/
https://www.ncbi.nlm.nih.gov/pubmed/23699397
http://dx.doi.org/10.1091/mbc.E12-10-0737

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