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Cells surviving fractional killing by TRAIL exhibit transient but sustainable resistance and inflammatory phenotypes
When clonal populations of human cells are exposed to apoptosis-inducing agents, some cells die and others survive. This fractional killing arises not from mutation but from preexisting, stochastic differences in the levels and activities of proteins regulating apoptosis. Here we examine the propert...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708725/ https://www.ncbi.nlm.nih.gov/pubmed/23699397 http://dx.doi.org/10.1091/mbc.E12-10-0737 |