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PakB binds to the SH3 domain of Dictyostelium Abp1 and regulates its effects on cell polarity and early development
Dictyostelium p21-activated kinase B (PakB) phosphorylates and activates class I myosins. PakB colocalizes with myosin I to actin-rich regions of the cell, including macropinocytic and phagocytic cups and the leading edge of migrating cells. Here we show that residues 1–180 mediate the cellular loca...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708727/ https://www.ncbi.nlm.nih.gov/pubmed/23699396 http://dx.doi.org/10.1091/mbc.E12-12-0883 |