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PakB binds to the SH3 domain of Dictyostelium Abp1 and regulates its effects on cell polarity and early development

Dictyostelium p21-activated kinase B (PakB) phosphorylates and activates class I myosins. PakB colocalizes with myosin I to actin-rich regions of the cell, including macropinocytic and phagocytic cups and the leading edge of migrating cells. Here we show that residues 1–180 mediate the cellular loca...

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Detalles Bibliográficos
Autores principales: Yang, Yidai, de la Roche, Marc, Crawley, Scott W., Li, Zhihao, Furmaniak-Kazmierczak, Emilia, Côté, Graham P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708727/
https://www.ncbi.nlm.nih.gov/pubmed/23699396
http://dx.doi.org/10.1091/mbc.E12-12-0883

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