Cargando…
PakB binds to the SH3 domain of Dictyostelium Abp1 and regulates its effects on cell polarity and early development
Dictyostelium p21-activated kinase B (PakB) phosphorylates and activates class I myosins. PakB colocalizes with myosin I to actin-rich regions of the cell, including macropinocytic and phagocytic cups and the leading edge of migrating cells. Here we show that residues 1–180 mediate the cellular loca...
Autores principales: | Yang, Yidai, de la Roche, Marc, Crawley, Scott W., Li, Zhihao, Furmaniak-Kazmierczak, Emilia, Côté, Graham P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708727/ https://www.ncbi.nlm.nih.gov/pubmed/23699396 http://dx.doi.org/10.1091/mbc.E12-12-0883 |
Ejemplares similares
-
A Myosin IK-Abp1-PakB Circuit Acts as a Switch to Regulate Phagocytosis Efficiency
por: Dieckmann, Régis, et al.
Publicado: (2010) -
Structure of the Dictyostelium Myosin-II Heavy Chain Kinase A (MHCK-A) α-kinase domain apoenzyme reveals a novel autoinhibited conformation
por: Ye, Qilu, et al.
Publicado: (2016) -
A disordered encounter complex is central to the yeast Abp1p SH3 domain binding pathway
por: Gerlach, Gabriella J., et al.
Publicado: (2020) -
Actin-binding protein G (AbpG) participates in modulating the actin cytoskeleton and cell migration in Dictyostelium discoideum
por: Lin, Wei-Chi, et al.
Publicado: (2015) -
Genetic deletion of ABP-120 alters the three-dimensional organization of actin filaments in Dictyostelium pseudopods
Publicado: (1995)