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Instantaneous inactivation of cofilin reveals its function of F-actin disassembly in lamellipodia
Cofilin is a key regulator of the actin cytoskeleton. It can sever actin filaments, accelerate filament disassembly, act as a nucleation factor, recruit or antagonize other actin regulators, and control the pool of polymerization-competent actin monomers. In cells these actions have complex function...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708729/ https://www.ncbi.nlm.nih.gov/pubmed/23676663 http://dx.doi.org/10.1091/mbc.E13-03-0156 |