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Dispelling urban myths about default uncertainty factors in chemical risk assessment – sufficient protection against mixture effects?
Assessing the detrimental health effects of chemicals requires the extrapolation of experimental data in animals to human populations. This is achieved by applying a default uncertainty factor of 100 to doses not found to be associated with observable effects in laboratory animals. It is commonly as...
Autores principales: | Martin, Olwenn V, Martin, Scholze, Andreas, Kortenkamp |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708776/ https://www.ncbi.nlm.nih.gov/pubmed/23816180 http://dx.doi.org/10.1186/1476-069X-12-53 |
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