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Selection of genes for gene-environment interaction studies: a candidate pathway-based strategy using asthma as an example

BACKGROUND: The identification of gene by environment (GxE) interactions has emerged as a challenging but essential task to fully understand the complex mechanism underlying multifactorial diseases. Until now, GxE interactions have been investigated by candidate approaches examining a small number o...

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Detalles Bibliográficos
Autores principales: Rava, Marta, Ahmed, Ismaïl, Demenais, Florence, Sanchez, Margaux, Tubert-Bitter, Pascale, Nadif, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708788/
https://www.ncbi.nlm.nih.gov/pubmed/23822639
http://dx.doi.org/10.1186/1476-069X-12-56