NTRK3 Is a Potential Tumor Suppressor Gene Commonly Inactivated by Epigenetic Mechanisms in Colorectal Cancer

NTRK3 is a member of the neurotrophin receptor family and regulates cell survival. It appears to be a dependence receptor, and thus has the potential to act as an oncogene or as a tumor suppressor gene. NTRK3 is a receptor for NT-3 and when bound to NT-3 it induces cell survival, but when NT-3 free,...

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Detalles Bibliográficos
Autores principales: Luo, Yanxin, Kaz, Andrew M., Kanngurn, Samornmas, Welsch, Piri, Morris, Shelli M., Wang, Jianping, Lutterbaugh, James D., Markowitz, Sanford D., Grady, William M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708790/
https://www.ncbi.nlm.nih.gov/pubmed/23874207
http://dx.doi.org/10.1371/journal.pgen.1003552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708790/
https://www.ncbi.nlm.nih.gov/pubmed/23874207
http://dx.doi.org/10.1371/journal.pgen.1003552

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