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Genome-scale Co-evolutionary Inference Identifies Functions and Clients of Bacterial Hsp90

The molecular chaperone Hsp90 is essential in eukaryotes, in which it facilitates the folding of developmental regulators and signal transduction proteins known as Hsp90 clients. In contrast, Hsp90 is not essential in bacteria, and a broad characterization of its molecular and organismal function is...

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Detalles Bibliográficos
Autores principales: Press, Maximilian O., Li, Hui, Creanza, Nicole, Kramer, Günter, Queitsch, Christine, Sourjik, Victor, Borenstein, Elhanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708813/
https://www.ncbi.nlm.nih.gov/pubmed/23874229
http://dx.doi.org/10.1371/journal.pgen.1003631