Exercise and diabetes have opposite effects on the assembly and O-GlcNAc modification of the mSin3A/HDAC1/2 complex in the heart

BACKGROUND: Exercise causes physiological cardiac hypertrophy and benefits the diabetic heart. Mammalian switch-independent 3A (mSin3A) and histone deacetylases (HDACs) 1 and 2 regulate hypertrophic genes through associations with the DNA binding proteins repressor element-1 silencing transcription...

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Detalles Bibliográficos
Autores principales: Cox, Emily J, Marsh, Susan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708830/
https://www.ncbi.nlm.nih.gov/pubmed/23835259
http://dx.doi.org/10.1186/1475-2840-12-101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708830/
https://www.ncbi.nlm.nih.gov/pubmed/23835259
http://dx.doi.org/10.1186/1475-2840-12-101

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