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The synaptic maintenance problem: membrane recycling, Ca(2+) homeostasis and late onset degeneration
Most neurons are born with the potential to live for the entire lifespan of the organism. In addition, neurons are highly polarized cells with often long axons, extensively branched dendritic trees and many synaptic contacts. Longevity together with morphological complexity results in a formidable c...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708831/ https://www.ncbi.nlm.nih.gov/pubmed/23829673 http://dx.doi.org/10.1186/1750-1326-8-23 |