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The synaptic maintenance problem: membrane recycling, Ca(2+) homeostasis and late onset degeneration

Most neurons are born with the potential to live for the entire lifespan of the organism. In addition, neurons are highly polarized cells with often long axons, extensively branched dendritic trees and many synaptic contacts. Longevity together with morphological complexity results in a formidable c...

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Detalles Bibliográficos
Autores principales: Bezprozvanny, Ilya, Hiesinger, Peter Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708831/
https://www.ncbi.nlm.nih.gov/pubmed/23829673
http://dx.doi.org/10.1186/1750-1326-8-23