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Fine Time Course Expression Analysis Identifies Cascades of Activation and Repression and Maps a Putative Regulator of Mammalian Sex Determination

In vertebrates, primary sex determination refers to the decision within a bipotential organ precursor to differentiate as a testis or ovary. Bifurcation of organ fate begins between embryonic day (E) 11.0–E12.0 in mice and likely involves a dynamic transcription network that is poorly understood. To...

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Detalles Bibliográficos
Autores principales: Munger, Steven C., Natarajan, Anirudh, Looger, Loren L., Ohler, Uwe, Capel, Blanche
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708841/
https://www.ncbi.nlm.nih.gov/pubmed/23874228
http://dx.doi.org/10.1371/journal.pgen.1003630