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Hierarchical Modeling for Rare Event Detection and Cell Subset Alignment across Flow Cytometry Samples
Flow cytometry is the prototypical assay for multi-parameter single cell analysis, and is essential in vaccine and biomarker research for the enumeration of antigen-specific lymphocytes that are often found in extremely low frequencies (0.1% or less). Standard analysis of flow cytometry data relies...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708855/ https://www.ncbi.nlm.nih.gov/pubmed/23874174 http://dx.doi.org/10.1371/journal.pcbi.1003130 |