A Single Immunization with MVA Expressing GnGc Glycoproteins Promotes Epitope-specific CD8+-T Cell Activation and Protects Immune-competent Mice against a Lethal RVFV Infection

BACKGROUND: Rift Valley fever virus (RVFV) is a mosquito-borne pathogen causing an important disease in ruminants often transmitted to humans after epizootic outbreaks in African and Arabian countries. To help combat the spread of the disease, prophylactic measures need to be developed and/or improv...

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Detalles Bibliográficos
Autores principales: López-Gil, Elena, Lorenzo, Gema, Hevia, Esther, Borrego, Belén, Eiden, Martin, Groschup, Martin, Gilbert, Sarah C., Brun, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708870/
https://www.ncbi.nlm.nih.gov/pubmed/23875044
http://dx.doi.org/10.1371/journal.pntd.0002309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708870/
https://www.ncbi.nlm.nih.gov/pubmed/23875044
http://dx.doi.org/10.1371/journal.pntd.0002309

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