Cargando…
A Single Immunization with MVA Expressing GnGc Glycoproteins Promotes Epitope-specific CD8+-T Cell Activation and Protects Immune-competent Mice against a Lethal RVFV Infection
BACKGROUND: Rift Valley fever virus (RVFV) is a mosquito-borne pathogen causing an important disease in ruminants often transmitted to humans after epizootic outbreaks in African and Arabian countries. To help combat the spread of the disease, prophylactic measures need to be developed and/or improv...
Autores principales: | López-Gil, Elena, Lorenzo, Gema, Hevia, Esther, Borrego, Belén, Eiden, Martin, Groschup, Martin, Gilbert, Sarah C., Brun, Alejandro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708870/ https://www.ncbi.nlm.nih.gov/pubmed/23875044 http://dx.doi.org/10.1371/journal.pntd.0002309 |
Ejemplares similares
-
NSG-Mice Reveal the Importance of a Functional Innate and Adaptive Immune Response to Overcome RVFV Infection
por: Michaely, Lukas Mathias, et al.
Publicado: (2022) -
MVA Vectored Vaccines Encoding Rift Valley Fever Virus Glycoproteins Protect Mice against Lethal Challenge in the Absence of Neutralizing Antibody Responses
por: López-Gil, Elena, et al.
Publicado: (2020) -
Efficacy of different DNA and MVA prime-boost vaccination regimens against a Rift Valley fever virus (RVFV) challenge in sheep 12 weeks following vaccination
por: Lorenzo, Gema, et al.
Publicado: (2018) -
An equine herpesvirus type 1 (EHV-1) vector expressing Rift Valley fever virus (RVFV) Gn and Gc induces neutralizing antibodies in sheep
por: Said, Abdelrahman, et al.
Publicado: (2017) -
Two monoclonal antibodies against glycoprotein Gn protect mice from Rift Valley Fever challenge by cooperative effects
por: Gutjahr, Benjamin, et al.
Publicado: (2020)