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Towards Predicting the Response of a Solid Tumour to Chemotherapy and Radiotherapy Treatments: Clinical Insights from a Computational Model

In this paper we use a hybrid multiscale mathematical model that incorporates both individual cell behaviour through the cell-cycle and the effects of the changing microenvironment through oxygen dynamics to study the multiple effects of radiation therapy. The oxygenation status of the cells is cons...

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Detalles Bibliográficos
Autores principales: Powathil, Gibin G., Adamson, Douglas J. A., Chaplain, Mark A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708873/
https://www.ncbi.nlm.nih.gov/pubmed/23874170
http://dx.doi.org/10.1371/journal.pcbi.1003120