CD40 Activation Rescues Antiviral CD8(+) T Cells from PD-1-Mediated Exhaustion

The intrahepatic immune environment is normally biased towards tolerance. Nonetheless, effective antiviral immune responses can be induced against hepatotropic pathogens. To examine the immunological basis of this paradox we studied the ability of hepatocellularly expressed hepatitis B virus (HBV) t...

Descripción completa

Detalles Bibliográficos
Autores principales: Isogawa, Masanori, Chung, Josan, Murata, Yasuhiro, Kakimi, Kazuhiro, Chisari, Francis V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708877/
https://www.ncbi.nlm.nih.gov/pubmed/23853599
http://dx.doi.org/10.1371/journal.ppat.1003490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708877/
https://www.ncbi.nlm.nih.gov/pubmed/23853599
http://dx.doi.org/10.1371/journal.ppat.1003490

Ejemplares similares