Genetic Selection for Context-Dependent Stochastic Phenotypes: Sp1 and TATA Mutations Increase Phenotypic Noise in HIV-1 Gene Expression

The sequence of a promoter within a genome does not uniquely determine gene expression levels and their variability; rather, promoter sequence can additionally interact with its location in the genome, or genomic context, to shape eukaryotic gene expression. Retroviruses, such as human immunodeficie...

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Detalles Bibliográficos
Autores principales: Miller-Jensen, Kathryn, Skupsky, Ron, Shah, Priya S., Arkin, Adam P., Schaffer, David V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708878/
https://www.ncbi.nlm.nih.gov/pubmed/23874178
http://dx.doi.org/10.1371/journal.pcbi.1003135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708878/
https://www.ncbi.nlm.nih.gov/pubmed/23874178
http://dx.doi.org/10.1371/journal.pcbi.1003135

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