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Mitochondrial Function in Human Neuroblastoma Cells Is Up-Regulated and Protected by NQO1, a Plasma Membrane Redox Enzyme

BACKGROUND: Recent findings suggest that NADH-dependent enzymes of the plasma membrane redox system (PMRS) play roles in the maintenance of cell bioenergetics and oxidative state. Neurons and tumor cells exhibit differential vulnerability to oxidative and metabolic stress, with important implication...

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Detalles Bibliográficos
Autores principales: Kim, Jiyeong, Kim, Su-Kyung, Kim, Hwa-Kyung, Mattson, Mark P., Hyun, Dong-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708898/
https://www.ncbi.nlm.nih.gov/pubmed/23874855
http://dx.doi.org/10.1371/journal.pone.0069030