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Mosaic VSGs and the Scale of Trypanosoma brucei Antigenic Variation

A main determinant of prolonged Trypanosoma brucei infection and transmission and success of the parasite is the interplay between host acquired immunity and antigenic variation of the parasite variant surface glycoprotein (VSG) coat. About 0.1% of trypanosome divisions produce a switch to a differe...

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Detalles Bibliográficos
Autores principales: Hall, James P. J., Wang, Huanhuan, Barry, J. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708902/
https://www.ncbi.nlm.nih.gov/pubmed/23853603
http://dx.doi.org/10.1371/journal.ppat.1003502