Transgenic Overexpression of Ephrin B1 in Bone Cells Promotes Bone Formation and an Anabolic Response to Mechanical Loading in Mice

To test if ephrin B1 overexpression enhances bone mass, we generated transgenic mice overexpressing ephrin B1 under the control of a 3.6 kb rat collagen 1A1 promoter (Col3.6-Tg(efnb1)). Col3.6-Tg(efnb1) mice express 6-, 12- and 14-fold greater levels of full-length ephrin B1 protein in bone marrow s...

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Detalles Bibliográficos
Autores principales: Cheng, Shaohong, Kesavan, Chandrasekhar, Mohan, Subburaman, Qin, Xuezhong, Alarcon, Catrina M., Wergedal, Jon, Xing, Weirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708903/
https://www.ncbi.nlm.nih.gov/pubmed/23874863
http://dx.doi.org/10.1371/journal.pone.0069051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708903/
https://www.ncbi.nlm.nih.gov/pubmed/23874863
http://dx.doi.org/10.1371/journal.pone.0069051

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