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Sodium Butyrate Protects against Severe Burn-Induced Remote Acute Lung Injury in Rats

High-mobility group box 1 protein (HMGB1), a ubiquitous nuclear protein, drives proinflammatory responses when released extracellularly. It plays a key role as a distal mediator in the development of acute lung injury (ALI). Sodium butyrate, an inhibitor of histone deacetylase, has been demonstrated...

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Detalles Bibliográficos
Autores principales: Liang, Xun, Wang, Ren-Su, Wang, Fei, Liu, Sheng, Guo, Feng, Sun, Li, Wang, Yong-Jie, Sun, Ye-Xiang, Chen, Xu-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708909/
https://www.ncbi.nlm.nih.gov/pubmed/23874764
http://dx.doi.org/10.1371/journal.pone.0068786