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Sodium Butyrate Protects against Severe Burn-Induced Remote Acute Lung Injury in Rats
High-mobility group box 1 protein (HMGB1), a ubiquitous nuclear protein, drives proinflammatory responses when released extracellularly. It plays a key role as a distal mediator in the development of acute lung injury (ALI). Sodium butyrate, an inhibitor of histone deacetylase, has been demonstrated...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708909/ https://www.ncbi.nlm.nih.gov/pubmed/23874764 http://dx.doi.org/10.1371/journal.pone.0068786 |