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Desmoglein-2-Integrin Beta-8 Interaction Regulates Actin Assembly in Endothelial Cells: Deregulation in Systemic Sclerosis

BACKGROUND: The inability of endothelial cells of patients affected by the diffuse form of Systemic sclerosis (SSc) to perform angiogenesis is a marker of the disease. We previously demonstrated that desmoglein-2 reduction is a major difference between (SSc)-microvascular endothelial cells (MVECs) a...

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Detalles Bibliográficos
Autores principales: Giusti, Betti, Margheri, Francesca, Rossi, Luciana, Lapini, Ilaria, Magi, Alberto, Serratì, Simona, Chillà, Anastasia, Laurenzana, Anna, Magnelli, Lucia, Calorini, Lido, Bianchini, Francesca, Fibbi, Gabriella, Abbate, Rosanna, Rosso, Mario Del
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708925/
https://www.ncbi.nlm.nih.gov/pubmed/23874518
http://dx.doi.org/10.1371/journal.pone.0068117